A standardised black seed oil preparation has been studied in people with fatty liver disease. Researchers reported changes in liver enzymes and ultrasound measurements.
Study design
Randomised, double-blind, placebo-controlled trial; 120 participants; standardised oil, 2.5 mL twice daily; three months.
Reported findings
A 2019 trial assigned 120 participants with non-alcoholic fatty liver disease to a standardised Nigella oil preparation or placebo for three months. The authors reported improvements in several liver-enzyme, lipid and ultrasound-steatosis measures.
Interpreting the result
The trial measured intermediate outcomes over a short period. It does not establish reversal of cirrhosis, prevention of liver failure or a general detoxification effect. Its standardised preparation may differ from a retail product in composition.
Why this study is useful
The study examined a standardised oil in a defined population over three months. Liver-enzyme and ultrasound changes are useful research measurements, while long-term progression requires longer follow-up. The result is best understood as a promising signal in that particular setting.
Source
Khonche A, Huseini HF, Gholamian M, Mohtashami R, Nabati F, Kianbakht S. Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease: A randomized, double-blind and placebo-controlled clinical trial. (2019).
Read the published study · Publisher / DOI
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