Black seed oil has attracted interest in joint-comfort research. A controlled knee-osteoarthritis trial reported improvements in pain and symptom scores over one month.
Study design
Randomised, double-blind, placebo-controlled trial; 116 enrolled, 106 completed; adults aged 50–70; oral oil versus placebo; one month.
Reported findings
A 2022 trial randomised 116 adults aged 50–70 with knee osteoarthritis to oral Nigella oil or placebo for one month; 106 completed it. The authors reported greater reductions in pain and WOMAC symptom scores with the oil.
Interpreting the result
One month is too short to establish durable benefit or structural disease modification. Reported pain and WOMAC changes should not be described as cartilage regrowth. The results apply to the studied osteoarthritis population, not every cause of knee pain.
Why this study is useful
Pain, stiffness and function are meaningful daily experiences. This trial measured short-term symptom change, giving it a practical comfort focus. It did not measure cartilage regrowth or show how long the effect lasts after the study period.
Source
Huseini HF, Mohtashami R, Sadeghzadeh E, Shadmanfar S, Hashem-Dabaghian F, Kianbakht S. Efficacy and safety of oral Nigella sativa oil for symptomatic treatment of knee osteoarthritis: A double-blind, randomized, placebo-controlled clinical trial. (2022).
Read the published study · Publisher / DOI
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