Standardised black seed oil and seasonal allergies: a 2024 trial

Illustration of Nigella seeds, amber oil and a botanical research notebook

Black seed oil is gaining attention in seasonal-allergy research. A controlled trial of a standardised oil formulation reported improvements in nasal and eye symptoms.

Study design

Randomised, double-blind, placebo-controlled study; 65 adults; 15 days; standardised oil plus piperine.

Reported findings

A 2024 trial followed 65 adults for 15 days. A standardised black seed oil capsule containing 5% thymoquinone, combined with piperine, improved nasal and eye symptom scores compared with placebo. The difference in IgE was not statistically significant.

Interpreting the result

The preparation included piperine and a specified thymoquinone concentration. The result applies to that combination over 15 days; it does not establish the same response from another oil or long-term allergy prevention.

Why this study is useful

This study puts black seed oil at the centre of a clearly defined question: can a specific oil formulation change the daily experience of seasonal allergies? Measuring both nasal and eye symptoms makes the findings relevant to how participants felt, while the ingredient details help explain exactly what was evaluated.

Source

Majeed A, Majeed S, Parameswarappa AK, Murali A, Gudimallam S, Siddegowda C, Chandrashekar H, Mundkur L. A randomized, double-blind, placebo-controlled study to evaluate the benefits of a standardized Nigella sativa oil containing 5% thymoquinone in reducing the symptoms of seasonal allergy. (2024).

Read the published study · Publisher / DOI

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