Black seed oil research includes how blood vessels respond to changes in blood flow. A small controlled trial found improvements in two vascular measurements.
Study design
Randomised controlled trial; 50 adults with cardiovascular risk factors; oil capsules versus placebo; two months.
Reported findings
A 2022 trial assigned 50 adults with cardiovascular risk factors to black seed oil capsules or placebo for two months. Flow-mediated dilation and nitric-oxide metabolites improved with the oil. Two vascular inflammatory markers, ICAM-1 and VCAM-1, did not differ significantly between groups.
Interpreting the result
The findings concern vascular measurements over two months. They do not establish fewer heart attacks or strokes, and the inflammatory-marker results were mixed.
Why this study is useful
Blood-vessel research goes beyond a single blood-pressure reading. Flow-mediated dilation measures how an artery responds to a change in blood flow. Studying this response alongside nitric-oxide metabolites gives researchers a way to explore how black seed oil may influence vascular function.
Source
Emamat H, Mousavi SH, Kargar Shouraki J, Hazrati E, Mirghazanfari SM, Samizadeh E, Hosseini M, Hadi V, Hadi S. The effect of Nigella sativa oil on vascular dysfunction assessed by flow-mediated dilation and vascular-related biomarkers in subject with cardiovascular disease risk factors: A randomized controlled trial. (2022).
Read the published study · Publisher / DOI
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